S. S. Keller

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We present microcantilever-based sensors for the characterization of biopolymer degradation by enzymes. Thin films of Poly(L-lactide) (PLLA) were spray-coated onto SU-8 cantilevers with well-known material properties and dimensions. The micromechanical sensors were immersed in solutions of proteinase K to investigate enzymatic degradation of PLLA. A(More)
We present a polymer microvalve that allows the detection of biopolymer degradation without the need of external energy. The valve is based on a polymer container filled with a colored marker solution and closed by a thin lid. This structure is covered by a film of poly(L-lactide) and degradation of the biopolymer triggers the release of the color which is(More)
A plug-and-play CD-like platform is used to perform a statistical detection of Platelet Derived Growth Factor (PDGF) proteins through aptamer-based surface functionalization of microcantilevers. When PDGF proteins bind to the aptamers, the cantilevers deflect. This deflection is monitored by optical readout heads from a DVD-ROM. The improved sensing(More)
We have integrated a micro-particle filter in a polymer cantilever to filter micro-particles from a fluid while simultaneously measuring the amount of filtered particles. In a 3,8 µm thick SU-8 cantilever a filter was integrated with pore sizes between 3 and 30 µm. The chip was inserted in a microfluidic system and water with differently sized(More)
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