S S Abidova

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  • S S Abidova
  • Eksperimental'naia i klinicheskaia farmakologiia
  • 2002
Ketamine (50 mg/kg, i.p.) increases the intensity of lipolysis in Wistar male rats, as manifested by increasing content of nonetherified fatty acids and cholesterol in the blood serum. This drug also enhances the lipid peroxidation (LPO) process, as manifested by the content of LPO products in the blood serum and in the liver and heart tissues. Propofol in(More)
In dogs with experimental peritonitis, accumulation of toxic metabolic products caused impairment in lipid metabolism. With reduction in pronouncement of endotoxemia under the influence of ultra-violet irradiation, the blood level of biologically active substances decreased, the process of lipolysis was suppressed.
Increase of lipolytic hormones and cAMP was revealed in experimental peritonitis. The amount of free fatty acids and the total protein content in the blood increased on the average by 50 and 40%, respectively. The blood free fatty acid content reduced to control values after hemosorption, the triglyceride concentration was normalized simultaneously, and the(More)
It has been shown in experiments on white rats that a single intraperitoneal injection of novodrine (1 mg/kg) stimulates respiration in myocardial mitochondria in a state of V0. Caprylate and palmitoyl carnitine were used as substrate. The drug reduces the rate of respiration in an active state so that the magnitude of respiratory control decreases. The(More)
Lipid metabolism (nonesterified fatty acids, triglycerides) was studied in experimental animals under halothane anesthesia in conditions of spontaneous respiration in dependence on oxygen content in the inhalation mixture. The results have shown that changes in blood lipid fractions depend on oxygen concentration in the inhalation mixture during anesthesia.(More)
Patients with hydatid disease of the liver were found to have disorders of lipid metabolism in the liver which led to increase in the amount of lipid peroxidation products and simultaneous decrease of blood serum antioxidant activity. An operation sharply induces the noted disturbances of lipid metabolism. A single administration of 1 ml of 10% alpha(More)
Effects of beta-adrenoblocker obsidan and selective beta-adrenoblocker cordanum on metabolism of fatty acids in the rat myocardium were studied. Obsidan increased the concentration of triglycerides and decreased that of nonesterified fatty acids in the myocardial tissue, reduced the amounts of ketone bodies, beta-oxybutyrate and acetoacetate, accelerated(More)
Content of cyclic adenosine monophosphate (cAMP), which involved in regulation of heart metabolism, was altered in myocardium depending on oxygen concentration in the inhalation mixture. Increase of oxygen concentration during gas anesthesia stimulated lipolysis and elevated cAMP content, while these parameters were lowered after decrease of oxygen content(More)