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Previous studies with a mycobacterial heat shock protein (hsp-65) have demonstrated some efficacy using cationic liposome-mediated gene transfer in murine i.p. sarcoma models. To further analyze the… (More)
We previously reported that treatment of intraperitoneal tumors with complexes of cationic lipid and noncoding plasmid DNA leads to the development of a specific, cytotoxic T-cell response… (More)
Gene delivery with cationic liposomes formed from the diamine-lipid DC-Chol and the neutral lipid DOPE has proven successful. New polyamine analogues of DC-Chol have been synthesised, formulated into… (More)
Enhanced gene transduction to the lung using cationic lipids could be attained through optimization of the structure of the lipids and the formulation of the cationic lipid:plasmid DNA (pDNA)… (More)