S. Richardson

J.A. Wells2
M.F. Lythgoe2
A.J. Schwarz2
J.M. O'Callaghan2
2J.A. Wells
2M.F. Lythgoe
2A.J. Schwarz
2J.M. O'Callaghan
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OBJECTIVE To use a unique obesity-discordant sib-pair study design to combine differential expression analysis, expression quantitative trait loci (eQTLs) mapping and a coexpression regulatory network approach in subcutaneous human adipose tissue to identify genes relevant to the obese state. STUDY DESIGN Genome-wide transcript expression in subcutaneous(More)
Routinely collected administrative data sets, such as national registers, aim to collect information on a limited number of variables for the whole population. In contrast, survey and cohort studies contain more detailed data from a sample of the population. This paper describes Bayesian graphical models for fitting a common regression model to a(More)
Creating non-equilibrium states of matter with highly unequal electron and lattice temperatures (T(ele)≠T(ion)) allows unsurpassed insight into the dynamic coupling between electrons and ions through time-resolved energy relaxation measurements. Recent studies on low-temperature laser-heated graphite suggest a complex energy exchange when compared to other(More)
BACKGROUND There is considerable evidence that tobacco control mass media campaigns can change smoking behaviour. In the UK, campaigns over the last decade have contributed to declines in smoking prevalence and been associated with falls in cigarette consumption among continuing smokers. However, it is less evident whether such campaigns can also play a(More)
  • N. Colgan, B. Siow, J.M. O'Callaghan, I.F. Harrison, J.A. Wells, H.E. Holmes +12 others
  • 2016
Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and related neurodegenerative conditions. We applied two diffusion models, diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI), to in vivo(More)
  • J.A. Wells, J.M. O'Callaghan, H.E. Holmes, N.M. Powell, R.A. Johnson, B. Siow +16 others
  • 2015
As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic proportions, there is an urgent need to develop effective treatment strategies to tackle the social and economic costs of this fatal condition. Dozens of candidate therapeutics are currently being tested in clinical trials, and compounds targeting the aberrant accumulation of(More)
Percutaneous arterial catheterisation is commonly undertaken for a range of diagnostic and interventional procedures. Iatrogenic femoral arteriovenous fistulas are an uncommon complication of these procedures. Most are asymptomatic and close spontaneously, but can rarely increase in size leading to the development of symptoms. We report a case of an(More)
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