S. R. Watt-Smith

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Gorham-Stout disease (GSD) is a rare, massively osteolytic condition which is associated with increased vascularity and an increase in osteoclast numbers. To determine the cellular and humoral mechanisms underlying the increase in osteoclast numbers and osteolysis in GSD, this study analysed circulating osteoclast precursor numbers and sensitivity to(More)
BACKGROUND Giant cell granuloma (GCG) is an osteolytic tumour of the jaw which is characterised by the presence of both mononuclear and multinucleated (osteoclast-like) giant cell components. The nature of these component cells and the pathogenesis of the extensive osteolysis associated with this lesion is uncertain. METHODS Using cell culture techniques(More)
Trigeminal sensory neuropathy is an important finding, often indicative of trauma but sometimes related to neoplasia, infections, demyelinating conditions, connective tissue disorders, other disorders, or, occasionally, drugs. This paper reports on a patient with sudden-onset trigeminal sensory neuropathy of the lip that proved to be drug-induced, secondary(More)
The role of percutaneous endoscopic gastrostomy (PEG) in patients undergoing resection of head and neck malignancy is well established. The procedure may be performed pre- or post-operatively with intravenous sedation or alternatively under general anaesthesia at the time of tumour resection. There are concerns as to the safety of PEG, particularly when(More)
The Oro-facial Digital Syndromes are well recognised, but confusion exists over their characteristics and nomenclature, especially as two new types have recently been described. Since there is no single feature that distinguishes one type from another, the authors recommend that classification be restricted to those sub-divisions with a known inheritance(More)
Cost efficiency of removing third molars in a practice specialising in minor oral surgery was compared to that of a hospital oral surgery department. A total of 100 patients treated in each locality were prospectively audited during the financial year 1989-90. Surgical complexity, waiting time, complications and patient satisfaction were compared. The(More)
The aim of this review is to outline the indications and provide a historical perspective of its development. The current complications are emphasized with the hope that greater caution and vigilance will lead to a reduction in their frequency. Finally, details of several techniques are described for gaining long-term venous access for critically ill or(More)