These studies examine the possibility that drugs (amphetamine and apomorphine) affecting dopamine metabolism might show conditioning properties and tests the hypothesis that dopaminergic activity might be responsible for any conditioning seen. If environmental cues can act as conditioning signals, affecting the activity of dopaminergic neurons, conditioning… (More)
Following 10 daily pairings of multiple conditioned stimuli with injection of cocaine (15 mg/kg), the presentation of the stimuli alone elicited behaviors in rats similar to those induced by cocaine. The behaviors included increased duration or frequency of rearing, sniffing, head bobbing, and horizontal locomotor activity (crossing). The level of the… (More)
A mother and son had peripheral neuropathy, abnormal elevation of serum IgM, and paraproteinemia. These patients may have a familial disorder of immune regulation with antibody-mediated neuropathy or a familial neuropathy with a secondary immune response.