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Adiponectin is a cytokine secreted specifically by adipocytes that has been proposed to enhance insulin sensitivity and prevent atherosclerosis. Adiponectin receptors (adipoR1 and adipoR2) are recently found in mice which act as receptors for globular and full-length adiponectin to mediate the fatty-acid oxidation and glucose uptake in muscle and liver. The(More)
High-affinity K+ transporters play an important role in K+ absorption of plants. We isolated a HAK gene from Aeluropus littoralis, a graminaceous halophyte. The amino acid sequence of AlHAK showed high homology with HAK transporters obtained from Oryza sativa (82%) and Hordeum vulgare (82%). When expressed in Saccharomyces cereviae WΔ3, AlHAK performed(More)
Cell death-inducing DFF45-like effectors a and c (CIDEa and CIDEc) are two members of the novel CIDE family of apoptosis-inducing factors. Except as pro-apoptotic proteins, it has been reported that CIDEa and CIDEc could be involved in lipid or fat metabolism. Here we first reported the cDNA cloning, chromosome mapping and expression analysis of CIDEa and(More)
Resistin is a member of resistin-like molecules (RELMs) and a hormone secreted from mature adipocytes in rodents and leukocytes in human. We now report the cloning and characterization of the full-length porcine resistin cDNA and gene. Sequence analysis indicated that the pig resistin cDNA sequence had an open reading frame of 330 bp encoding a 12 kDa(More)
Kruppel-like factors (KLF) and the early growth response factor 2 (EGR2) are important zinc finger transcription factors in vertebrates. We have cloned the full length coding sequence (CDS) of porcine KLF5, KLF7 and EGR2, which are 1374, 909 and 1416 bp, respectively. KLF4, KLF5 and EGR2 were then chromosomally mapped to porcine 1q28–29, 11q13–14 and(More)
Angiopoietin-like protein 3 and -4 (ANGPTL3 and -4) are two members of angiopoietin-like proteins (ANGPTLs), which have the signature structure of the angiopoietin family but cannot bind to the TIE2 receptor. It has been reported that they both affect lipid metabolism by inhibiting the activity of lipoprotein lipase (LPL). Here we report the cDNA cloning,(More)
K. N. Barish, S. Batsouli, S. J. Bennett, M. Bertaina, A. Chikanian, T. M. Cormier, P. Fachini, B. Fadem, S. Q. Feng, L. E. Finch, N. K. George, S. V. Greene, P. Haridas, J. C. Hill, A. S. Hirsch, R. Hoversten, H. Z. Huang, H. Jaradat, T. Lainis, J. G. Lajoie, Q. Li, L. S. Liu, H. Long, C. Maguire, R. D. Majka, T. E. Miller, M. G. Munhoz, J. L. Nagle, A.(More)