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Rho GTPases play an essential role in the regulation of many cellular processes. Although various guanine nucleotide exchange factors (GEFs) are involved in the activation of Rho GTPases, the precise mechanism regulating such activity remains unclear. We have examined whether ERK1/2 are involved in the phosphorylation of GEF-H1, a GEF toward RhoA, to(More)
This paper presents an assessment method of the risks of occupational accidents based on fuzzy logic. The purpose of this work was to create a methodological instrument that can semiquantitatively assess the risk of occupational accidents for different industrial and site activities and to identify the most efficient intervention measures that can be taken(More)
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