Learn More
the date of receipt and acceptance should be inserted later Abstract. When a column generation approach is applied to decomposable mixed integer programming problems, it is standard to formulate and solve the master problem as a linear program. Seen in the dual space, this results in the algorithm known in the nonlinear programming community as the(More)
For content based image retrieval using shape descriptors, most approaches so far extract shape information from a seg-mentation of the image. Shape features derived based on a specific segmentation are not suitable for images containing complex structures. Further, static segmentation based approaches are useful only for a small set of queries. In this(More)
In the past decade, significant progress has been achieved in developing generic primal heuristics that made their way into commercial mixed integer programming (MIP) solver. Extensions to the context of a column generation solution approach are not straightforward. The Dantzig-Wolfe decomposition principle can indeed be exploited in greedy, local search,(More)
MOTIVATION We present a pipeline for the pre-processing, quality assessment, read distribution and methylation estimation for methylated DNA immunoprecipitation (MeDIP)-sequence datasets. This is the first MeDIP-seq-specific analytic pipeline that starts at the output of the sequencers. This pipeline will reduce the data analysis load on staff and allows(More)
In this paper, we propose models, algorithms, and implementation details of an approach that extract the most relevant entity rankings from large datasets. This is done in a fully automated way, as with large amounts of structured data, beyond well understood databases (schemas), manual solutions do not scale. The core task of our approach is to decide(More)
To depict the largest picture of a core promoter interactome, we developed a one-step DNA-affinity capture method coupled with an improved mass spectrometry analysis process focused on the identification of low abundance proteins. As a proof of concept, this method was developed through the analysis of 230 bp contained in the 5'long terminal repeat (LTR) of(More)
  • 1