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Towards a systems toxicology-based risk assessment, we investigated molecular perturbations accompanying histopathological changes in a 28-day rat inhalation study combining transcriptomics with(More)
BACKGROUND Tobacco harm reduction, substituting less harmful tobacco products for combustible cigarettes, is a complementary approach for smokers who would otherwise continue to smoke. The Philip(More)
BACKGROUND Cigarette smoking increases the risk of chronic diseases; heating instead of burning tobacco can lower these risks. This study (with 984 adult American smokers) examined whether favorable(More)
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