S M Wheeley

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We have studied a group of children born to HBsAg+ mothers, resident in the English West Midlands; none of the children had sought medical attention for hepatitis B-related problems. Forty-two out of 48 children born to HBeAg+ mothers were HBsAg+. Among these children, the mean age of the HBeAg+ girls was significantly lower than that of the HBeAg+ boys (P(More)
Perinatal transmission of hepatitis B virus (HBV) from HBsAg carrier mothers who were HBeAg+, antiHBe+, or negative for both HBe markers, was interrupted using either 4 doses of vaccine, or one dose of hepatitis B immunoglobulin (HBIG) at birth, combined with 4 doses of vaccine. In those infants who received HBIG at birth, the antiHBs titre was(More)
In this paper, using a pluralistic perspective on the psyche, I consider theoretical formulations concerned with the development of the self in relation to the environment. This includes discussion about how the infant interacts with its maternal environment before birth and how observation of the foetus in the womb and infant research have important(More)
In this paper I explore ways in which the fundamental balance between life and death forces is portrayed within the Oedipus myth, showing how there are times when, as theorists, we are blind to the on-going dynamic polarities contained within the myth. Using clinical case material I explore the vicissitudes of the theme of infanticide and the impact of the(More)
During the two year period 1986/87, 271 babies were born to hepatitis B surface atigen carrier mothers in the English West Midlands. Babies were allocated sequentially into either treatment Group A (4 doses of HBVax, Merck Sharp & Dohme, 10 mcg. i.m, at birth, 1, 2 and 6 months) or treatment Group B (250 I.U. hepatitis B immunoglobulin (HBIG) at birth,(More)
A four-dose vaccination schedule was used to interrupt perinatal transmission of hepatitis B virus from carrier mothers to their babies. Of 49 babies immunised and successfully followed up, 43 (88%) became immune: 15 out of 21 (71%) of babies born to HBeAg + mothers became immune, the other 6 becoming the only carrier babies in the study. Without(More)
We have recently followed up a group of infants born in 1974-76 who became hepatitis B carriers as a result of perinatal transmission. 92% of these infants (11/12) remain carriers 9 years later. None have clinical evidence of liver disease. On follow up serum transaminases are well within the normal range, and are significantly lower (p < 0.05) than in the(More)
Fifteen children who had become positive for hepatitis B surface antigen (HBsAg) by perinatal transmission were traced and re-examined after a mean of 8.1 years; all had been born in England to mothers from ethnic minorities who were carriers of HBsAg. Fourteen of the children remained carriers of HBsAg; of these, more girls than boys developed antibody to(More)
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