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BACKGROUND Frail patients with non-Hodgkin's lymphoma (NHL) are generally excluded from clinical trials and not even treated. The aim of this study was to evaluate the efficacy and tolerability of vinorelbine and prednisone in frail elderly patients with NHL. PATIENTS AND METHODS Thirty consecutive frail elderly patients were entered in a phase II study(More)
Sir, We read with great interest the article by Arnould et al (2006). In their study, they investigated by immunohistochemistry (IHC) immune cell response during neoadjuvant primary systemic therapy with trastuzumab and docetaxel in patients with IHC 3 þ HER2-positive primary breast cancer. Trastuzumab treatment was associated with significantly increased(More)
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