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BACKGROUND AND OBJECTIVES The purpose of this study was to investigate the acceptability and therapeutic efficacy of a preoperative single administration of long-acting 5-hydroxytryptamine type 3 (5-HT 3) receptor antagonist in an orally disintegrating tablet formulation, ramosetron, in breast cancer patients. METHODS Two hundred and forty women, ASA(More)
The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information(More)
BACKGROUND Sevoflurane is a widely used inhalation anesthetic, but there are no studies on its effect on the wound-healing process. This study was undertaken to evaluate the effect of exposure time to sevoflurane on wound healing. METHOD Male Sprague-Dawley rats were used. Two circular full-thickness skin defects 8 mm in diameter were made on the dorsum(More)
A series of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for antibacterial activity. The 6-fluoro-2-methyl-1-prenyl-1,4-dihydro-7-(3,5-dimethylpiperazinyl)-4-oxo-3-quinolinecarboxylic acid (14f) exhibited the most potent antibacterial activity against gram-positive bacteria among the total 32 derivatives.(More)
A benign hepatic adenoma in a young woman taking oral contraceptives for 7 years is reported. The diagnosis must be suspected in any young woman taking oral contraceptive agents who develop signs and symptoms of acute cholecystitis with hepatomegaly or mass, or when signs and symptoms of non-traumatic intraabdominal hemorrhage are present. Rupture of the(More)
References 1 Mombaerts I, Goldschmeding R, Schlingemann RO, Koornneef L. What is orbital pseudotumour? Surv Ophthalmol 1996; 41: 66–78. 2 Rubin PA, Foster CS. Etiology and management of idiopathic orbital inflammation. Am J Ophthalmol 2004; 138: 1041–1043. 3 Scott IU, Siatkowski RM. Idiopathic orbital myositis. Curr Opin Rheumatol 1997; 9: 504–512. 4 Gordon(More)
The gluteus maximus myocutaneous flap is modified to obviate the necessity of a skin graft to the donor defect. This is a sufficiently large flap which, in the event of a recurrence, can be rerotated. The design and surgical technique of this flap for ischial and sacral pressure sores are described. This flap was used for 36 pressure sore without loss of(More)