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The chemotactic and random mobility functions of twelve selectively IgA-deficient patients were evaluated by a method using agarose gel. A severe polymorphonuclear cellular chemotactic defect was found in ten out of twelve patients, but only five of them also showed a marked associated impairment of random locomotory function. Furthermore, in one subject,(More)
IgG- and IgA-rheumatoid factor like activities have been found in 4 out of 8 i.v. Ig preparations and in 1 i.m. Ig studied as control. In 2 i.v. Igs as well as in the 1 i.m., these RF-like activities were both present. These RF-like activities seem to be essential constituents of low m.w. aggregates, disappearing at acid pH. Their presence could perhaps be(More)
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