S L Bridgers

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BACKGROUND Nonrheumatic atrial fibrillation is common among the elderly and is associated with an increased risk of stroke. We investigated whether anticoagulation with warfarin would reduce this risk. METHODS We conducted a randomized, double-blind, placebo-controlled study to evaluate low-intensity anticoagulation with warfarin (prothrombin-time ratio,(More)
Several investigators have reported cognitive deficits associated with symptomatic carotid artery disease. This paper reports the findings of a study investigating cognitive deficits associated with asymptomatic carotid stenosis. Experimental subjects consisted of six patients who, in the course of routine physical examinations, showed carotid bruits and,(More)
The results of electroencephalographic screening of 3225 inpatients from a community general hospital psychiatric service were reviewed. When patients with a prior diagnosis of epilepsy were excluded, epileptiform abnormalities were discovered in 2.6% of patients. Patients younger than age 25 years and patients with a diagnostic impression of anorexia(More)
The potential of transcranial magnetic stimulation (TMS) to cause undesired or unexpected effects on cognition and other cerebral functions has received only limited study, although extensive clinical use has suggested that obvious problems are unlikely. Evidence so far accumulated suggests that exposure to TMS in the expected clinical situations will have(More)
BACKGROUND Cerebral infarction in patients with atrial fibrillation may vary from being clinically silent to catastrophic. The prevalence of silent cerebral infarction and its effect as a risk factor for symptomatic stroke are important considerations for the evaluation of patients with atrial fibrillation. METHODS AND RESULTS This Veterans Affairs(More)
One hundred forty-four scalp ictal EEGs from 54 patients were analyzed independently by three electroencephalographers for side and lobe of seizure onset. Observers did not know the patients' identities. Accuracy was determined by depth EEG. We found 58 to 60% agreement between observers for lobe, and 64 to 74% for side, of seizure onset; 21 to 38%(More)
Surgical manipulation in the region of the carotid sinus resulted in diffuse electroencephalographic slowing in two patients, despite the absence of bradycardia or hypotension. Direct observation confirmed the absence of carotid compression. The effect was abolished by infiltration of lidocaine hydrochloride into the carotid sinus area. Carotid clamping in(More)
Superior sagittal sinus thrombosis, documented by cerebral angiography, was demonstrated by indium-111 platelet scintigraphy in a 40-year-old man presenting with seizures and intracerebral hematoma. Early scintigraphy demonstrated focal increased indium-111 activity at the two ends of the thrombus, while later scintigraphy showed diffuse increased activity(More)
To assess possible persistent cerebral effects, we acquired EEG, measured serum prolactin, and administered cognitive and motor tests before and after transcranial magnetic stimulation of 30 healthy adults. We found no detrimental effects on EEG or test performance. A slight but statistically significant decline in serum prolactin lacked correlation with(More)
One recognized limitation of carotid Doppler/ultrasound is its accuracy in differentiating occlusion from near-total occlusion of the internal carotid artery, which is a crucial issue in management decisions. Clinical histories were reviewed in 58 patients with apparent occlusion of an internal carotid artery diagnosed by Doppler/ultrasound who also(More)