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This article provides an overview of the field of bioinformatics and its implications for the various participants. Next-generation issues facing developers (programmers), users (molecular biologists), and the general public (patients) who would benefit from the potential applications are identified. The goal is to create awareness and debate on the(More)
To be effective, knowledge-based systems should have a mechanism for representing and reasoning with uncertainty. Bayesian networks are used quite frequently for this purpose, and the final decision suggested by the expert system is a function of the relative strength of various causal relationships embodied in the network and the decision rule used. The(More)
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