S K Zyryanov

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AIM To evaluate clinical and economic efficacy of schizophrenia treatment with three forms of paliperidone (peroral form, intramuscular injections once a month and once in three month). MATERIAL AND METHODS Pharmacoeconomic analysis based on the results of earlier foreign randomized clinical studies on paliperidone in treatment of schizophrenia was(More)
40 experimental rats had 80 silicon prostheses implanted in the hind legs for the purpose of studying the peculiarities of a capsule developing round the implant over one to twelve weeks. The silicon implant was found to help develop a smooth-walled inter-tissue capsule with a concentric pattern of collagen fibres and fibroblasts without the development of(More)
Infectious pathology in the neonatal period is of the leading causes of neonatal morbidity and mortality. Urinary tract infection occurs in 23% of all infectious diseases. The treatment of infectious diseases mainly employs eradication therapy, mostly with anti-bacterial drugs. In practice, the therapy of infants frequently employs prescribing off-label(More)
The authors discuss the mechanism of action, effectiveness, and safety of intranasal glucocorticosteroids (inGCS) used to treat acute, recurrent and chronic rhinosinusitis (RS). The last version of the European guidelines concerning the application of inGCS assigns the highest level of evidence-Ia and the highest strength of recommendations-A to these(More)
Neovascular age-related macular degeneration (AMD) is the leading cause of vision loss in older patients. An important role in angiogenesis is played by regulatory mechanisms (an increase in the number of proliferating endothelial and stromal cells and morphological alterations in the vascular network) induced by factors from the vascular endothelial growth(More)
The paper discusses the non-anticoagulant properties of unfractionated heparin and enoxaparin and their relation to their chemical structures. It is emphasized that enoxaparin has multiple, often interrelated, non-anticoagulant effects that can complement its antithrombotic activity and enhance the efficiency of therapy in patients receiving the drug for(More)
AIM Clinical and economic examinations were made to study whether it is appropriate to use antiplatelet therapy (APT) with ticagrelor in combination with acetylsalicylic acid (ASA) versus a combination of clopidogrel and ASA in patients with acute coronary syndrome (ACS) following coronary artery bypass surgery (CABS). MATERIAL AND METHODS A budget impact(More)
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