S K Dhar

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Potassium embelate, 2,5-dihydroxy, 3-undecyl-1, 4-benzoquinone, from Embelia ribes Burm. was subjected to toxicity evaluation which included subacute, chronic, reproductive toxicity testing and teratological investigations in laboratory animals (mice, rats and monkeys). The results did not indicate adverse effects suggesting that potassium embelate is a(More)
  • S K Dhar
  • 1995
Trans-anethole was studied for antifertility activity in rats at dose levels of 50 mg, 70 mg and 80 mg/kg po. Dose-dependent activity was observed, a 100% anti-implantation activity being achieved at 80 mg/kg, po. The compound showed a significant estrogenic activity and did not possess anti-estrogenic, progestational, anti-progestational, androgenic or(More)
Some features of the natural history of malaria in holoendemic areas can be explained by the presence of acquired immunity. There is also evidence that transmission of humoral antibodies in utero from the immune mother plays some part in the transient protection of the offspring. Little is known about the importance of a genetic factor.The possibility of(More)
The effect of alcoholic extracts of the aerial parts of fagonia cretica on estrous cycle and implantation in female albino rats was studied, It induced random omission of heat phase in eh estrous cycle and exhibited 100% anti implantation activity without exhibiting any toxic manifestation, However it was found to have some strong androgenic(More)
AIM To search for female contraceptive agents. METHODS 2-Hydroxy-3-methyl-1, 4-naphthoquinone monosemicarbazone (HMNQS) and 2-hydroxy-1, 4-naphthoquinone monothiosemicarbazone (HNQTS) were screened for anti-implantation activity in rats. RESULTS Both compounds showed a dose-dependent activity, and HNQTS was more potent. An 100% anti-implantation(More)
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