S. K. Alexander

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BACKGROUND Corticobasal degeneration (CBD) is a complex neurodegenerative disorder. Accurate diagnosis is increasingly important, with the advent of clinical trials of drugs aimed at modifying the underlying tau pathology. CBD often presents with a 'corticobasal syndrome' including impairments of movement and cognition. However, patients with similar(More)
In nano-medicine, mesoporous silicon particles provide efficient vehicles for the dissemination and delivery of key proteins at the micron scale. We propose a new quality-control method for the nanopore structure of these particles, based on image analysis software developed to automatically inspect scanning electronic microscopy (SEM) images of(More)
Validation of the new consensus criteria for the diagnosis of corticobasal degenerationValidation of the new consensus criteria for the diagnosis of corticobasal degeneration' General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of(More)
The behavioural variant of frontotemporal dementia (bvFTD) is characterised by personality change with a decline in cognition. We describe two patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukencephalopathy (CADASIL) who presented with behavioural phenotypes similar to bvFTD. The first patient presented with(More)
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