S. James Zinreich

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A biomechanical model of the brain is presented, using a finite-element formulation. Emphasis is given to the modeling of the soft-tissue deformations induced by the growth of tumors and its application to the registration of anatomical atlases, with images from patients presenting such pathologies. First, an estimate of the anatomy prior to the tumor(More)
PURPOSE To evaluate the dimensions of specific white matter tracts in the brainstems (region of brain thought to be least affected) of children with holoprosencephaly by using diffusion tensor magnetic resonance (MR) imaging and to correlate these abnormalities with forebrain malformation severity and neurologic deficit severity. MATERIALS AND METHODS(More)
For the theoretic advantages of 3T units to translate to improved diagnostic quality, careful attention must be paid to optimization of pulse sequences and development of clinically feasible imaging protocols. RARE sequences continue to be the choice for routine clinical imaging of the head and neck; although exquisite T2W images are afforded, T1W imaging(More)
We evaluated 5 consecutive patients with subdural grid electrodes (including placement over the left basal temporal region) for focal resections for control of intractable epilepsy. All 5 had language dysfunction when we performed cortical stimulation over the basal temporal region (the inferior temporal gyrus, the parahippocampal gyrus) using a systematic(More)
Myasthenia gravis (MG) commonly presents with weakness and fatigability of the lids and extraocular muscles, which respond to treatment with anticholinesterase medication. However, certain intracranial mass lesions may mimic these features of MG; alternatively, MG may mask the signs of a coexistent intracranial mass. We describe 8 patients originally(More)
We present an image overlay system to aid needle insertion procedures in computed tomography (CT) scanners. The device consists of a display and a semitransparent mirror that is mounted on the gantry. Looking at the patient through the mirror, the CT image appears to be floating inside the patient with correct size and position, thereby providing the(More)
The effect on the brain of the sex-linked recessive form of adrenoleukodystrophy was studied in 40 boys, 4-18 years old. All underwent computed tomography (CT) scanning; six underwent magnetic resonance (MR) imaging. MR showed a high sensitivity in demonstrating white matter disease. Auditory pathway disease was characterized as involvement of the lateral(More)
OBJECTIVE We present a 2D image overlay device to assist needle placement on computed tomography (CT) scanners. MATERIALS AND METHODS The system consists of a flat display and a semitransparent mirror mounted on the gantry. When the physician looks at the patient through the mirror, the CT image appears to be floating inside the body with correct size and(More)
PURPOSE To delineate the relationship between the optic nerves and the posterior paranasal sinuses using CT data. METHODS Direct coronal sinus CT scans of 150 consecutive patients with chronic inflammatory sinus disease were reviewed by two radiologists. Axial oblique reconstructions along the course of the optic nerve were obtained for the first 100(More)
To evaluate the spatial accuracy of a rapid interactive method of transferring computed tomographic (CT) information between its display on a computer screen to its source (test object, operating field), a multidimensional computer combined with a six-jointed position-sensing mechanical arm was tested with a Plexiglas model consisting of 50 rods of varied(More)