S.J. O'Shea

Learn More
BACKGROUND Moderate to severe psoriasis is associated with increased alcohol intake and excessive mortality from alcohol-related causes. Alcohol biomarkers provide an objective measure of alcohol consumption. Carbohydrate-deficient transferrin (CDT) is the single most sensitive and specific alcohol biomarker. OBJECTIVES To assess alcohol consumption in a(More)
BACKGROUND Dermatological teaching has traditionally stressed that complete skin examination is essential in the assessment of patients with potential skin disease. OBJECTIVES To determine whether complete skin examination results in increased diagnoses of skin malignancies that would not have been discovered otherwise. METHODS New patients (n = 483)(More)
BACKGROUND There are limited data on the use of ustekinumab outside of clinical trials. OBJECTIVES To assess the efficacy and safety of ustekinumab in patients with severe psoriasis attending 10 dermatology centres in the U.K. and Ireland. METHODS A retrospective case-note review of 129 patients with psoriasis treated with ustekinumab. RESULTS(More)
Survival from melanoma is influenced by several, well-established clinical and histopathological factors, e.g. age, Breslow thickness and microscopic ulceration. We (the Section of Epidemiology and Biostatistics, University of Leeds) have carried out research to better understand the biological basis for these observations. Preliminary results indicated a(More)
  • 1