S Iu Garmonov

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The authors elaborated noninvasive method to diagnose acetylation phenotype through photocolorimetric studying kinetics of sulfadimesine urinary excretion. Suggestion is approach to people protection through selection of inductors which purposefully increase individual activity of N-acetyltransferase.
New methods for detecting the acetylation phenotype have been developed for therapeutic monitoring using isoniazid as the pharmacogenetic marker. The study is carried out with 4-chloro-5,7-dinitrobenzofurane by direct spectrophotometry, high performance liquid and thin-layer chromatography. The methods proved to be highly sensitive, selectively detecting(More)
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