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BACKGROUND AND PURPOSE Orolingual angioedema (OA) is an uncommon but potentially life-threatening complication of treatment with recombinant tissue plasminogen activator (rt-PA; alteplase) during acute ischaemic stroke. This study aimed to determine the incidence of rt-PA-related OA in an Asian stroke population and the risk of pre-stroke anti-hypertensive(More)
BACKGROUND The presence of oligoclonal bands (OCBs) in cerebrospinal fluid (CSF) often implies the involvement of the humoral immune response in the disease process. We compared three methods of electrophoresis to determine the frequency and pattern of OCBs in Chinese patients with various neurologic diseases. METHODS CSF samples and matched serum samples(More)
OBJECTIVE To determine the therapeutic effect of levodopa/benserazide and tolcapone on gait in patients with advanced Parkinson's disease. METHODS Instrumental gait analysis was performed in 38 out of 40 patients with wearing-off phenomenon during a randomized, double-blind, placebo-controlled trial of tolcapone. RESULTS Gait analysis disclosed a(More)
During the last decade, progressive achievements in haemodynamics have shown that radial artery pulse pressure can be used to estimate the vascular properties of the internal organs. Clinical experiments have shown that slow and regular respiration has a large effect on the heart rate variability (HRV). This phenomenon is called respiratory sinus arrhythmia(More)
BACKGROUND AND PURPOSE Anticoagulant and antiplatelets for prevention of ischaemic stroke and cardiovascular diseases may increase the risk of intracerebral hemorrhage (ICH). This study aimed to investigate the influence of pre-ICH use of anticoagulant and antiplatelets on ICH patients. METHODS Consecutive patients with acute spontaneous ICH registered in(More)
OBJECTIVES Early diagnosis and management of intracranial dural arteriovenous fistulae (DAVF) may prevent the occurrence of stroke. This study aimed to identify the best carotid duplex sonography (CDS) parameters for screening DAVF. METHODS 63 DAVF patients and 170 non-DAVF patients received both CDS and conventional angiography. The use of seven CDS(More)
Decreased mitochondrial Complex I activities and a 4,977-bp deletion in mitochondrial DNA (mtDNA) have been reported in patients with Parkinson's disease. Based on the assumption of possible links between this 4,977-bp deletion and the etiology of Parkinson's disease, we analyzed mtDNA of blood cells from 15 patients with young-onset Parkinson's disease(More)
Background and objectives:Oxidative stress and the insulin-resistant state are thought to be key components in the pathogenesis of pediatric nonalcoholic fatty liver disease (NAFLD). Heme oxygenase (HO) is important in the defense against oxidative stress. This study aimed to assess the association of HO-1 gene promoter polymorphism and insulin resistance(More)
BACKGROUND To improve dose-related fluctuations in patients with Parkinson's disease, the efficacy of selegiline, a selective inhibitor of monoamine oxidase B, was determined. METHODS Twenty parkinsonian patients were selected for a short-term, single-blind, cross-over trial. Each patient received one of the two brands of selegiline, Parkryl (Mei-Shih),(More)
In this study, we investigated a fluidic system that adheres to new concepts of energy production. To improve efficiency, cost, and ease of manufacture, a millimetrically scaled device that employs a droplet-based co-axial fluidic system was devised to complete alkali-catalyzed transesterification for biodiesel production. The large surface-to-volume ratio(More)