S I D'iakov

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Peculiarities of the protective effect of ciprofloxacin and lomefloxacin were studied and the optimal regimens of their use were determined in multifactor experiments on albino mice infected with finally dispersed aerosol of the virulent strain of the European subspecies of Francisella tularensis. As for protective effect, the fluoroquinolones provided high(More)
A new procedure for rapid determination of the levels of antibiotic sensitivity in pathogenic microorganisms with the use of fluorescent antibodies is described. The procedure was developed with the use of a model of the vaccinal strains of Bacillus anthracis. It is based on determination of the microbial antibiotic resistance with the method of serial(More)
Comparative antibacterial activity and protective efficacy of ciprofloxacin, pefloxacin and lomefloxacin were estimated in a model of anthrax. The MICs of the three drugs determined by the method of serial dilutions for three vaccinal strains of Bacillus anthracis were 0.5 to 1.0 microgram/ml. The protective efficacy of the chemotherapeutics in experimental(More)