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Biotic and abiotic stress lead to elevated levels of jasmonic acid (JA) and its derivatives and activation of the biosynthesis of nicotine and related pyridine alkaloids in cultivated tobacco (Nicotiana tabacum L.). Among the JA-responsive genes is NtPMT1a, encoding putrescine N-methyl transferase, a key regulatory enzyme in nicotine formation. We have(More)
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