S.-H. Yen

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Genetic screening of 171 patients with frontotemporal lobar degeneration disclosed 14 patients, across nine pedigrees, with mutations in the intron to exon 10 in the tau gene, a region regulating the splicing of exon 10 via a stem loop mechanism. Thirteen of these patients had the +16 splice site mutation and one had the +13 splice site mutation. Affected(More)
AIM Tau protein is a prominent component of paired helical filaments in Alzheimer's disease (AD) and other tauopathies. While the abnormal phosphorylation of tau on serine and threonine has been well established in the disease process, its phosphorylation on tyrosine has only recently been described. We previously showed that the Src family non-receptor(More)
—This paper presents a novel hierarchical and grid based reconfigurable optical-wireless network (GROW-Net) architecture. GROW-Net supports scalable and flexible integration of a large scale wireless mesh network in a municipal environment. Under the GROW-Net architecture, a joint evolution strategy is proposed to allow graceful upgrades in both optical(More)
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