Learn More
BACKGROUND Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS). We assessed the epidemiology of SARS in Hong Kong. METHODS We included 1425 cases reported up to April 28, 2003. An integrated database was constructed(More)
In Hong Kong, kindergartens and primary schools were closed when local transmission of pandemic (H1N1) 2009 was identified. Secondary schools closed for summer vacation shortly afterwards. By fitting a model of reporting and transmission to case data, we estimated that transmission was reduced approximately 25% when secondary schools closed.
BACKGROUND Timely estimation of the transmissibility of a novel pandemic influenza virus was a public health priority in 2009. METHODS We extended methods for prospective estimation of the effective reproduction number (Rt) over time in an emerging epidemic to allow for reporting delays and repeated importations. We estimated Rt based on case(More)
OBJECTIVE To describe the epidemiology, clinical and laboratory findings, and outcomes of patients presenting locally with dengue. DESIGN Retrospective review of case records. SETTING Public hospitals, Hong Kong. PATIENTS Medical records of all laboratory-confirmed dengue patients admitted to public hospitals during 1998 to 2005 were reviewed(More)
BACKGROUND Experience from influenza pandemics suggested that convalescent plasma treatment given within 4 to 5 days of symptom onset might be beneficial. However, robust treatment data are lacking. METHODS This is a multicenter, prospective, double-blind, randomized controlled trial. Convalescent plasma from patients who recovered from the 2009 pandemic(More)
BACKGROUND Despite World Health Organization recommendations, the rate of 23-valent pneumococcal (PPV) and influenza (TIV) vaccination among elderly persons in Hong Kong, China, is exceptionally low because of doubts about effectiveness of vaccination. The efficacy of dual vaccination remains unknown. METHODS From 3 December 2007 to 30 June 2008, we(More)
BACKGROUND Experience from treating patients with Spanish influenza and influenza A(H5N1) suggested that convalescent plasma therapy might be beneficial. However, its efficacy in patients with severe pandemic influenza A(H1N1) 2009 virus (H1N1 2009) infection remained unknown. METHODS During the period from 1 September 2009 through 30 June 2010, we(More)
OBJECTIVE To investigate the prevalence and characteristics of abusive drug exposure among non-fatal motor vehicle driver casualties presenting to a designated trauma centre in Hong Kong. DESIGN Cross-sectional study. SETTING Designated trauma centre/regional accident and emergency department in Hong Kong. SUBJECTS Non-fatal motor vehicle driver(More)
OBJECTIVE To investigate the situation among Chinese patients with regard to infection with multiple strains of Helicobacter pylori. METHODS Biopsy specimens for culture of H. pylori were obtained from gastric antrum, body and fundus of 20 patients during endoscopic investigation of upper gastrointestinal symptoms. H. pylori was identified by culture from(More)
Norovirus outbreaks occur worldwide every year and have become more frequent over the last few years. There were extensive outbreaks in Hong Kong from May to July 2006 and our aim was to describe nosocomial outbreaks from 1 May 2006 to 31 July 2006 in this retrospective observational study. A total of 38 confirmed norovirus outbreaks involving 218 patients(More)