S H Hegarty

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Background:The homeobox containing transcription factor MSX2 is a key regulator of embryonic development and has been implicated to have a role in breast and pancreatic cancer.Methods:Using a selection of two- and three-dimensional in vitro assays and tissue microarrays (TMAs), the clinical and functional relevance of MSX2 in malignant melanoma was(More)
Hereditary hemochromatosis (HH) results in increased iron absorption and subsequent deposition in tissue. This condition occurs predominantly in individuals of Northern European and Celtic origin with Ireland having one of the highest allele frequencies in the world. This study examines the hypothesis that homozygosity for either the C282Y or H63D mutations(More)
Ulster Medical Society Junior Members Forum Thursday 12th December 2013 Whitla Medical Building, Queen’s University Belfast. ASPIRIN THERAPY IS ASSOCIATED WITH REDUCED MORTALITY IN PATIENTS WITH ACUTE LUNG INJURY Boyle AJ, Digangi A, Mottram LJ, Hamid U, McNamee L, White G, Cross LJM, McNamee J, O’Kane C, McAuley DM. Introduction: Platelet activation has a(More)
Keynote address: " Marfan syndrome and related disorders: from gene to therapy " Prof. 3 AED Pregnancy register, UK and Ireland Antiepileptic drug (AED) exposure during pregnancy increases the risk of major congenital malformations (MCMs). The risk magnitude varies by AED exposure. We provide results from the UK and Ireland Epilepsy and Pregnancy Registers,(More)
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