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Schizophrenia is a psychotic disorder characterized by functional dysconnectivity or abnormal integration between distant brain regions. Recent functional imaging studies have implicated large-scale thalamo-cortical connectivity as being disrupted in patients. However, observed connectivity differences in schizophrenia have been inconsistent between(More)
This paper summarizes the neuroimaging methods in the diagnostic assessment process that have been applied to neuropsychiatric studies. Here, we outline the signal processing challenges in structural and functional neuroimaging methods and discuss the specific difficulties in multisite data analysis for the diagnosis of neuropsychiatric disorders.(More)
Many studies have shown that schizophrenia patients have aberrant functional network connectivity (FNC) among brain regions, suggesting schizophrenia manifests with significantly diminished (in majority of the cases) connectivity. Schizophrenia is also associated with a lack of hemispheric lateralization. Hoptman et al. (2012) reported lower(More)
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