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To evaluate the possible use of mutant ras as a biomarker for lung cancer, we have analyzed "normal appearing" lung tissue, lung tumor, lung metastases and sputum samples from patients with non-small cell lung cancer (NSCLC). As a control, we used lung tissue and sputum samples from patients without oncological diseases or lung disorders. Our analyses were(More)
During the past 22 years, the operability rate has been 62.2% for patients 60 years or older, with cancer of the cardia (319/475). The resectability rate has been 66.2% (211/319). Proximal resection of the stomach with resection of the lower third of the esophagus was performed on 156 patients, and gastrectomy on 65. During the last 5 years the operative(More)
Patients with malignant skin melanoma were given different kinds of immunotherapy; nonspecific immunotherapy with BCG vaccine, adaptive immunotherapy with methotrexate or phytohemagglutinin activated autolymphocytes, and also a combination of polychemotherapy with BCG. The state of cell immunity was determined prior to, during and at the end of the therapy,(More)
The material of 70 patients with lung adenocarcinomas radically operated at the All-Union Cancer Research Centre is analyzed. The spread of tumour expressed in terms of TNM system (I group--T1-3 N0M0--37 patients, II group--T1-3 N1M0--18 patients, III group--T1-3 N2M0--11 patients, IV group--T1-3 N1M1--4 patients) and its ultrastructure served as criteria.(More)
163 operated on patients were divided into 2 groups: the 1st group--those surviving 5 years without recurrence (44.2%) and the 2nd group--those dying earlier from the tumour progression (55.8%). Central carcinoma was in 104, peripheral one in 59 cases. The number of dark cells (DC) and the degree of desmosome development revealed ultrastructurally have the(More)
Some prognostic signs of surgical treatment of carcinoma of the lung are analysed. The stability and paramount importance of the integral clinical factor "extension of the tumor" is shown. The ultrastructural features of adenocarcinoma and squamous-cell carcinoma of the lungs influencing the disease prognosis were revealed. It is shown that electron(More)
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