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In 1980, Belyaeva et al. found in Drosophila melanogaster the ecs (ecdysterone sensitivity) locus, later designated BR-C (Broad-Complex). This locus plays a key role in the reaction cascade of ecdysterone-regulated development. The gene BR-C was cloned by Chao and Guild (1986) and Belyaeva et al. (1987). To conduct "walking along the chromosome" in… (More)