S Fernández-Cebrián

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INTRODUCTION Complex IV or cytochrome c oxidase (COX) deficiency is the most common disorder involving complexes of the respiratory chain in the pediatric age. Exceptionally, it has been reported in association with Alpers syndrome or Alpers disease, and with its variant named progressive neuronal degeneration with liver disease or Alpers-Huttenlocher(More)
We report a child with recurrent syncopal episodes who underwent head-up tilt testing according to a protocol that includes continuous and noninvasive measurement of brain oxygen saturation. We demonstrated significant cerebral hypoxemia during syncope without concomitant systemic hemodynamic disturbances. This response to head-up tilt test suggested the(More)
OBJECTIVE The objective was to evaluate prospectively the role of hyperventilation in the development of neurocardiogenic syncope in children during head-upright tilt testing (HUTT). STUDY DESIGN Tilt testing was performed in 34 children (mean age 10.6 years) with clinical suspicion of syncope. Respiratory rate and end-tidal carbon dioxide pressure were(More)
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