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Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide.
There are indications for changes in glutamate metabolism in relation to depression or suicide. The glutamate-glutamine cycle and neuronal/glial glutamate transporters mediate the uptake of theExpand
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Different stress-related gene expression in depression and suicide.
OBJECTIVE Suicide occurs in some, but not all depressed patients. So far, it remains unknown whether the studied stress-related candidate genes change in depression, suicide or both. The prefrontalExpand
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Prefrontal alterations in GABAergic and glutamatergic gene expression in relation to depression and suicide.
People that committed suicide were reported to have enhanced levels of gene transcripts for synaptic proteins in their prefrontal cortex (PFC). Given the close association of suicide with majorExpand
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Neurotransmitters and neuropeptides in depression.
Abstract There are no specific structural neuropathological hallmarks found in the brain of patients with mood disorders. The described alterations confirm, however, a neurodevelopmentalExpand
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