S D Vimadalal

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Sixty-four lung tumors were evaluated for the presence of immunoreactive neuron-specific enolase (NSE), bombesin (Bn), and chromogranin (Cg) to assess their value as markers for neuroendocrine cells in the histologic diagnosis of pulmonary neoplasms. Staining was correlated with the presence and density of neurosecretory granules (number of neurosecretory(More)
Prior animal models of cholesterol gallstone formation have been criticized for their dissimilarity to the conditions of humans with gallstones. We present a new hamster model of cholesterol cholelithiasis that more closely approximates the human situation. Sixty female Golden Syrian hamsters (average weight 83.2 +/- 3.4 g) were allocated to six groups of(More)
Viable mononuclear and epithelial cells were dispersed from human colonic tissue by treatment with collagenase and ethylene diamino-tetra acetate (EDTA) and separated by centrifugal elutriation. Using a single cell cytotoxic assay, functional endogenous and interferon responsive mononuclear cytotoxic cells were detected. Compared to peripheral blood(More)
High calcitonin levels noted on a totally healthy 49-year-old man participating in a calcitonin control project led to a presumptive diagnosis of medullary carcinoma. Complete thyroid studies augmented by selective catheterization and quantitative calcitonin studies confirmed the clinical impression of medullary carcinoma. Surgery was recommended and a(More)
Gastrointestinal cytomegalovirus (CMV) infection usually occurs in immunosuppressed patients and has recently been reported in patients with the acquired immune deficiency syndrome (AIDS). Serological evidence of CMV infection and a variety of traumatic and infectious gastrointestinal disorders are known to occur in nonimmunosuppressed homosexual males.(More)
UNLABELLED We previously reported a hamster model for cholesterol gallstone formation and prophylaxis. The aim of this study was to validate a model for dissolution of cholesterol gallstones by testing bile acids used in patients. Sixty hamsters were allocated to six groups of ten; Group I received the standard diet (.8mg cholesterol/gram food) and Groups(More)
Thirty-six lymphoreticular neoplasms involving the stomach were studied by immunologic technics (particularly immunoperoxidase on paraffin sections) for the localization of immunoglobulins, lysozyme, and alpha one-antitrypsin. Fifteen of 29 (52%) primary gastric lymphomas marked as B-cell lymphomas and only one primary gastric lymphoma of true histiocytic(More)
The role of biliary secretions was studied in the development of neoplasms in the small intestine and colon of rats treated with 1,2-dimethylhydrazine (DMH). Sixty-eight female Sprague-Dawley rats underwent either no operative procedure or choledochojejunostomy with or without a Roux-en-Y exclusion. All animals then received weekly subcutaneous injections(More)
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