S. D. Makhortov

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The detection and quantification of low-abundance somatic DNA mutations by high-throughput sequencing is challenging because of the difficulty of distinguishing errors from true mutations. There are several approaches available for analyzing somatic point mutations and small insertions or deletions, but an accurate genome-wide assessment of somatic(More)
Lattice-based algebraic structures containing semantics of production-logic inference on a type hierarchy in an object-oriented system with an additional relation are introduced. Specific features of these structures, such as closedness, possibility of equivalent transformations, existence of logical reduction, are studied. It is shown how to apply the(More)
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