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Accepted for publication 25 July 1991 Abstract Background-In animal models of circulatory shock and heart failure concentrations of the endogenous opioid peptide # endorphin are raised and opioid receptor blockade improves haemodynamic variables and survival. This study was performed to identify whether acute myocardial ischaemia provokes the release of #(More)
Background-Endogenous opioids have a tonic inhibitory effect on sympathetic tone and have been implicated in the pathophysiology of vasodepressor syncope. Plasma a endorphin concentrations increase after vasodepressor syncope induced by exercise or by fasting. Aims-To take frequent samples for plasma/a endorphin estimation during tilt testing, and to(More)
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