S. Cabanillas

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STUDY QUESTION Could cell therapy using autologous peripheral blood CD133+ bone marrow-derived stem cells (BMDSCs) offer a safe and efficient therapeutic approach for patients with refractory Asherman's syndrome (AS) and/or endometrial atrophy (EA) and a wish to conceive? SUMMARY ANSWER In the first 3 months, autologous cell therapy, using CD133+ BMDSCs(More)
OBJECTIVE To investigate the engraftment and proliferation of superparamagnetic iron oxide nanoparticles (SPIOs)-labeled human CD133(+) bone marrow-derived stem cells (BMDSCs) in an animal model of Asherman syndrome (AS). DESIGN Prospective experimental animal study. SETTING University research laboratories. ANIMAL(S) Nonobese diabetic mice (strain(More)
OBJECTIVE To determine the clinical value of preimplantation genetic diagnosis for aneuploidy screening (PGD-A) in women of advanced maternal age (AMA; between 38 and 41 years). DESIGN This was a multicenter, randomized trial with two arms: a PGD-A group with blastocyst transfer, and a control group with blastocyst transfer without PGD-A. SETTING(More)
OBJECTIVE To analyze the transcriptomic profile of endometrial gene alterations during the window of implantation in infertile obese patients. DESIGN Multicenter, prospective, case-control study. SETTING Three academic medical centers for reproductive medicine. PATIENT(S) Infertile patients, stratified into body mass index (BMI) categories according(More)
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