S C Sukhdeo

Learn More
Mesenchyme cells and their processes are found in the cerebral ganglia of the parasitic flatworm, Fasciola hepatica. The mesenchyme cell processes are found in two specialized associations within the ganglion: (i) as lamellae-like multilayer sheaths encircling the cerebral ganglia and separating it from the surrounding parenchyma cells, and (ii) invaginated(More)
1. Stretch stimulation of the abdominal muscle receptor organ of the lobster Homarus americanus initiated spike discharge of its tonic sensory neuron (SR1). This sensory response evoked a series of tonic postural reflex responses in the motor neurons that innervate the superficial extensor and flexor muscles of the abdominal postural system. The type of(More)
The head region of the trematode parasite Fasciola hepatica contains 3.47 +/- 0.42 pmol/mg wet wt. of serotonin as measured by high-performance liquid chromatography coupled to electrochemical detection. The head region includes the cerebral ganglia, the transverse commissure and associated nervous tissue that innervates the musculature of the oral sucker,(More)
The localization of FMRFamide-related peptide (FaRP) immunoreactivity was determined during different stages of development of the rat tapeworm Hymenolepis diminuta. In the adult worm (14 days old), FaRP immunostaining was most intense in the scolex and concentrated in the central nervous system (cerebral ganglia and transverse commissures) and around the(More)
During ontogenetic development in the definitive host, the cerebral ganglia of the parasitic flatworm Fasciola hepatica lose their cell rind integrity and develop specialized nerve processes. The organization and cytological features of the central nervous system were examined during three developmental stages in the parasitic life cycle of F. hepatica to(More)
Acetylcholinesterase activity was found in the cell bodies and extracellularly in the neuropile of the cerebral ganglia of the adult trematode parasite, Fasciola hepatica. Within neuronal cell bodies of the cerebral ganglion, acetylcholinesterase reaction product was found in the endoplasmic reticulum, in the cisternae of the Golgi apparatus, and in(More)
An ultrastructural study of the organization and fine structure of the nervous system of the parasitic flatworm Fasciola hepatica was undertaken. The brain consists of paired cerebral ganglia, located just posterior to the oral sucker, that are connected by a transverse commissure which crosses over the dorsal surface of the pharynx. The cell bodies of the(More)
Acetylcholine, cholinergic agonists and acetylcholinesterase inhibitors significantly decrease the amplitude and frequency of spontaneous longitudinal muscle contractions in Fasciola hepatica. In order of their effects on the inhibition of muscle contractions, the cholinergic agonists can be ranked as nicotine greater than carbachol greater than(More)
  • 1