S. B. Serebryani

  • Citations Per Year
Learn More
Partial reduction of thrombin disulfide bridges with dithiothreitol in the absence of denaturants inhibits the fibrinogen clotting but not the esterase activity of the enzyme. The clotting activity reappears on spontaneous air reoxidation of thrombin. As a result of the reaction with dithiothreitol, two disulfide bonds are cleaved in thrombin molecule(More)
The pyrocarbonate (I) was taken 20% excess and was added to the reaction mixture in the form of a I M solution in acetone. The time and temperature of the reaction was varied according to the reactivity of the amino acid. The Pboc derivatives of the amino acids were isolated by the method generally used in similar cases [5, 6] and were crystallized from the(More)
  • 1