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BACKGROUND/AIMS Glial fibrillary acidic protein is an intermediate filament first identified in the brain in astrocytes. This study examines glial fibrillary acidic protein immunoreactivity in normal and damaged rat livers. Glial fibrillary acidic protein-gene-expression in Ito cells, endothelial cells, Kupffer cells, and hepatocytes is also analyzed. (More)
Ito cells (lipocytes, stellate cells) are regarded as the principle matrix-producing cell of the liver and have been shown recently to express glial fibrillary acidic protein, an intermediate filament typically found in glia cells of the nervous system. The present study examines 1) whether Ito cells of rat liver express central nervous system typical(More)
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