S. Aguín Losada

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Glioblastoma multiforme (GBM) is the most common brain tumor in adults. The role of high in normal-1 (HIN-1) as a potential biomarker in combating this disease is being described for the first time in this study. A combination of O6-methylguanine DNA methyltransferase (MGMT) and HIN-1 methylation could be a possible biomarker in therapy choice.(More)
Dear Editor: We refer to the interesting letter from Dr Esposito and colleagues in France, describing 2 siblings who lived in severe domestic squalor (1). One was an unmarried woman, aged 61 years; the other was her brother, aged 58 years and suffering from a physical handicap. The authors state that Diogenes syndrome is rare in a pair of siblings and that(More)
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