S.A. Nick McElhinny

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Eukaryotic replication [1, 2] begins at origins and on the lagging strand with RNA-primed DNA synthesis of a few nucleotides by polymerase a, which lacks proofreading activity. A polymerase switch then allows chain elongation by proofreading-proficient pol d and pol 3. Pol d and pol 3 are essential, but their roles in replication are not yet completely(More)
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