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Phosphagen kinases catalyze the reversible dephosphorylation of guanidino phosphagens such as phosphocreatine and phosphoarginine, contributing to the restoration of adenosine triphosphate concentrations in cells experiencing high and variable demands on their reserves of high-energy phosphates. The major invertebrate phosphagen kinase, arginine kinase, is(More)
The crown ether-catalyzed glycosylation of phenol, 4-methoxyphenol, and 4-nitrophenol was studied under phase transfer conditions in solid–liquid system. The asymmetric dibenzocrown esters are superior to [3.3]dibenzo-18-crown-6 and 15-crown-5 in the catalysis of these reactions.
Glycosylation of benzothiazolone-2, 5-methylbenzoxazolone-2, and benzothiazolone-2 with the full acetate of α-D-glucosaminyl chloride in the phase transfer systems investigated (solid-organic solvent and aqueous alkali-organic solvent) regioselectively leads to the corresponding N-β-D-glucosaminides, which is proved by 1H NMR spectroscopy and X-ray analysis.
Glycosylation of various phenols with α-D-glucosaminyl chloride peracetate in a solid phase–liquid system catalyzed by crown compounds was studied. The highest yields of aryl β-glycosides were observed at room temperature in acetonitrile using anhydrous potassium carbonate as a base. The optimum phenol–glycosyl donor–base–crown ether ratio was 1 : 1 : 1 :(More)
An analysis of the data presented in Tables 2 and 3 shows that all of the preparations used for the tests have antimicrobial activity with respect to all of the test microbes used for the investigation. The compounds have the most pronounced action on inducers of intestinal infections (Shigella, Salmonella) and some representatives of quasi-pathogenic(More)
The use of crown ethers for a phase transfer-catalyzed synthesis of heteroaromatic glycosides of N-acetylglucosamine was studied. The solid-liquid system and catalysis by 15-crown-5 were found to provide for both the 100% conversion of α-D-glucosaminyl chloride peracetate and a high reaction rate. The interaction of α-D-glucosaminyl chloride peracetate and(More)
Pharmacological examination of macrocyclic polyethers (crown ethers) has shown that some of them display quite high physiological activity [i, 3, 5-7, 12, 14, 24]. The variety of crown ethers which have been synthesized require in turn systematic studies of similar structures in order to establish relationships between the type of substituents, the size of(More)
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