S A Aristarkhova

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An injection of a alpha-tocopherol and analog devoid of the lateral chain (C1) at a dose of 90 mg/kg of body weight to experimental animals increases the levels of natural antioxidants and lipid oxidation in mouse liver 4- and 4.5-fold, respectively. The effects of alpha-tocopherol on the lipids possessing a high antiradical activity and containing the(More)
The changes in the level of natural antioxidants and lipid oxidation in normal mouse liver and after injection of the natural antioxidant alpha-tocopherol were studied. The level of natural antioxidants and lipid oxidation were increased 1--2-fold within 24 hrs; after alpha-tocopherol injection these parameters were increased 37- and 39-fold, respectively.(More)
The effect of exogeneous (egg) lecithin on peroxidation of microsomal lipids was studied with the view of elucidating the role of various components of lipid substrate in the overall oxidation rate of the lipids. The following processes were studied a) NADPH-dependent microsomal lipid peroxidation in the presence of lecithin; b) ascorbate-dependent(More)
The effect of dipalmitoyl phosphatidylcholine (DPPC) and its structural fragments--phosphatidic acid (PA) and choline chloride--on the ascorbate-dependent mice liver microsomal lipid peroxidation (LP) has been studied at the different LP rate. At DPPC, PA and choline chloride introduction into the incubation medium before the onset of peroxidation induction(More)
Variations in lipid peroxidation were observed in individual membrane structures of liver cells after burns of the IIIb degree involving 15-20% of rat body surface and studied within 1 hr, 1 day and 7 days after the thermal injury. First of all and mainly the systems of lipid peroxidation were stimulated in microsomes and mitochondria. The lysosomal lipids(More)