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1. The quaternary carbon analogue of acetylthiocholine (AThCh), 3.3-dimethylbuthylthioacetate (DMBTA), has been synthesized and subjected to a preliminary investigation as substrate for cholinesterase (ChE). 2. Acetylcholinesterase was found to hydrolyze DMBTA at 25% of the rate of AThCh when both substrates were used in a concentration of 6×10−4M. For(More)
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