Sílvia Cristina Dias Pinto

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PURPOSE During cystitis, increased innervation of the bladder by sensory nerves may contribute to bladder overactivity and pain. The mechanisms whereby cystitis leads to hyperinnervation of the bladder are, however, poorly understood. Since TRP channels have been implicated in the guidance of growth cones and survival of neurons, we investigated their(More)
This article describes the use of the 2D wavelet transform to estimate the multiscale gradient of two types of cortical sulci, from which two potentially discriminating features, namely the gradient mean magnitude and entropy of its orientation distributions, are calculated. The obtained results coroborates the potential of such multiscale geometrical(More)
This work presents a new approach for the 3D human facial expressions analysis. Our methodology is based on 2D and 3D wavelet transforms, which are used to estimate multi-scale features from real a face acquired by a 3D scanner. The proposed methodology starts by considering a dataset composed by faces displaying seven different facial expressions. An(More)
This paper presents a new approach for the morphome-trical characterization of brain structures using shape features calculated from normal fields. An orientable surface representation of the brain structure is derived allowing the estimation of the corresponding normal field without the need of a parameterized surface. In fact, the normal field is(More)
The cation channel TRPM8 plays a central role in the somatosensory system, as a key sensor of innocuously cold temperatures and cooling agents. Although increased functional expression of TRPM8 has been implicated in various forms of pathological cold hypersensitivity, little is known about the cellular and molecular mechanisms that determine TRPM8(More)
BACKGROUND This feasibility study established an experimental protocol to evaluate brain activation patterns using fluorodeoxyglucose positron emission tomography ((18F)FDG-PET) during volume-induced voiding and isovolumetric bladder contractions in rats. METHODS Female Sprague-Dawley rats were anaesthetized with urethane and underwent either(More)
The accurate determination of the sex of human skeletal remains is a critical challenge in forensic pathology and skeletal anthropology. The pelvis and the skull are the most commonly used skeletal sites for determining the sex of skeletons. In the skull, the supraorbital region, which includes the supraorbital margin, is considered a specific sexually(More)
This work presents the application of advanced analysis processes and datamining to images produced by scanning probe microscopy in polymers samplers. These techniques are applied to two specific problems: statistical characterization of polydispersivity in films of poly (o-methoxyaniline) (POMA) and morphological analysis of substrates of polymers used to(More)
TRPM4 is a calcium-activated but calcium-impermeable non-selective cation (CAN) channel. Previous studies have shown that TRPM4 is an important regulator of Ca2+-dependent changes in membrane potential in excitable and non-excitable cell types. However, its physiological significance in neurons of the central nervous system remained unclear. Here, we report(More)
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