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RSK2(Ser227) at N-terminal kinase domain is a potential therapeutic target for multiple myeloma.

• Yuji Shimura, Junya Kuroda, +13 authors Masafumi Taniwaki
• Molecular cancer therapeutics
• 2012

Multiple myeloma is an entity of cytogenetically and genetically heterogenous plasma cell neoplasms. Despite recent improvement in the treatment outcome of multiple myeloma by novel… (More)

Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia.

• Mio Yamamoto-Sugitani, Junya Kuroda, +14 authors Masafumi Taniwaki
• Proceedings of the National Academy of Sciences…
• 2011

Bone marrow (BM) microenvironment (BMME) constitutes the sanctuary for leukemic cells. In this study, we investigated the molecular mechanisms for BMME-mediated drug resistance and BM lodgment in… (More)

Cyclosporine A for chemotherapy-resistant subcutaneous panniculitis-like T cell lymphoma with hemophagocytic syndrome.

• Shinsuke Mizutani, Junya Kuroda, +13 authors Masafumi Taniwaki
• Acta haematologica
• 2011

Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a rare subtype of non-Hodgkin lymphoma for which a definitive therapeutic strategy has not been established yet. We report a case of… (More)

FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors

• Miki Kiyota, Junya Kuroda, +11 authors Masafumi Taniwaki
• Apoptosis
• 2013

PP2A activator FTY720 has been shown to possess the anti-leukemic activity for chronic myelogenous leukemia (CML), however, the cell killing mechanism underlying its anti-leukemic activity has… (More)

Low ADAMTS-13 activity during hemorrhagic events with disseminated intravascular coagulation.

• Yoshiaki Chinen, Junya Kuroda, +11 authors Masafumi Taniwaki
• International journal of hematology
• 2013

Disseminated intravascular coagulation (DIC) is a life-threatening complication, and its control is essential for therapeutic success. Recombinant human soluble thrombomodulin alfa (rTM) is a novel… (More)

Comprehensive cytogenetic study of primary cutaneous gamma-delta T-cell lymphoma by means of spectral karyotyping and genome-wide single nucleotide polymorphism array.

• Mio Yamamoto-Sugitani, Junya Kuroda, +11 authors Masafumi Taniwaki
• Cancer genetics
• 2012

Primary cutaneous gamma-delta T-cell lymphoma (PCGD-TCL), which originates from activated mature gamma-delta T cells with a cytotoxic phenotype is a rare T-cell lymphoproliferative disease. The… (More)

A compact low-temperature hydrogen ion beam apparatus for in situ physical property measurements.

• Ryuko Nakayama, Naoto Suzuki, Mitsuhiko Maesato, Takuya Nagaoka, Makoto Arita, Hiroshi Kitagawa
• The Review of scientific instruments
• 2017

A new compact low-temperature hydrogen ion beam apparatus has been developed for in situ physical property measurements. Introduction of hydrogen can significantly alter the physical properties of… (More)

Suppression of SERPINA1-albumin complex formation by galectin-3 overexpression leads to paracrine growth promotion of chronic myelogenous leukemia cells.

• Ryuko Nakayama, Junya Kuroda, +12 authors Masafumi Taniwaki
• Leukemia research
• 2014

Galectin-3 is induced in chronic myelogenous leukemia (CML) cells by co-culture with bone marrow stromal cells, making paracrine growth promotion of CML cells in conditioned medium (CM) from… (More)

Rheumatoid arthritis/methotrexate-associated primary cutaneous diffuse large B-cell lymphoma, leg type.

• Yosuke Matsumoto, Shigeo Horiike, +13 authors Masafumi Taniwaki
• Internal medicine
• 2014

This report concerns a 62-year-old man with primary cutaneous diffuse large B-cell lymphoma (PCLBCL), leg type that developed during methotrexate (MTX) treatment for rheumatoid arthritis (RA).… (More)

Close pathogenetic relationship between ocular immunoglobulin G4-related disease (IgG4-RD) and ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma

• Ryuko Nakayama, Yosuke Matsumoto, +15 authors Masafumi Taniwaki
• Leukemia & lymphoma
• 2014

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