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BACKGROUND Oral neurofibromas are peripheral nerve sheath tumors, similar to schwannomas. Histological variations in oral neurofibromas are relatively uncommon. CASE PRESENTATION Here, we present a case of unique variation in the observed characteristics of a neurofibroma, with no relation to neurofibromatosis type-1 or von Recklinghausen disease of the(More)
BACKGROUND Metastasis via the lymphatic system is promoted by lymphangiogenesis. Alterations of the lymphatic channels during the progression of metastasis to regional lymph nodes (LNs) remain unexplored. To examine whether tumor-induced LN lymphangiogenesis controls metastasis to regional LNs, we investigated cervical LN metastasis in a mouse model of oral(More)
To elucidate the involvement of intercellular adhesion molecule-1 (ICAM-1) in the migration of lymphocytes to the oral mucosal epithelium in a rat model of acute graft-versus-host disease (AGVHD), we investigated (1) ICAM-1 and major histocompatibility complex (MHC) class II expression by keratinocytes (KCs) and their role in the epithelial infiltration of(More)
Dear Sirs, Although haematopoietic stem cell transplantation (HSCT) is being used for haematopoietic reconstitution following highdose chemotherapy for malignancy, it involves some serious transplant-related complications (1, 2), such as graft-versushost disease (GVHD) and vascular disorders (such as veno-occlusive disease (VOD), pulmonary vasculopathy,(More)
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