Ryuji Hayashi

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Bradykinin (BK) is a major kinin with well-documented pharmacological properties including vascular leakage and induction of a variety of cytokines. However, the intracellular signalling mechanisms by which BK induced proinflammatory cytokine production have not been fully elucidated. This study investigated the role of the extracellular signal-regulated(More)
UNLABELLED Aims/Introduction:  It has been reported that metabolic syndrome is associated with impaired lung function, and abdominal obesity is regarded as the most important determinant of this association. We evaluated the association between a component of metabolic syndrome, indices of body composition, including the total adipose tissue content, lean(More)
The inhibition of DNA damage response pathway seems to be an attractive strategy for cancer therapy. It was previously reported that in rodent cells exposed to heat stress, cell growth was promoted by the activity of DNA-dependent protein kinase (DNA-PK), an enzyme involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair.(More)
INTRODUCTION Chronic necrotizing pulmonary aspergillosis usually occurs in mildly immune-compromised hosts or those with underlying pulmonary disease. The radiographic pattern of chronic necrotizing pulmonary aspergillosis is typically a progressive upper lobe cavitary infiltrate with pleural thickening. We report here an atypical case of chronic(More)
INTRODUCTION Miliary brain metastasis is an extremely rare form of brain metastasis which can present with atypical imaging findings. We report the case of a patient with miliary brain metastasis of lung cancer showing calcification in metastatic lesions. CASE PRESENTATION A 68-year-old Japanese woman was diagnosed with lung adenocarcinoma. Brain computed(More)
We report an educational autopsy case of combined pulmonary fibrosis and emphysema. Radiological patterns of the upper lung were considered as mostly emphysema, but pathological observation revealed significant interstitial fibrosis of usual interstitial pneumonia as a major pathology. The patient eventually developed acute exacerbation of background(More)
A 38-year-old Japanese male was referred to our hospital with abnormal chest X-ray results and severe Coombs-positive hemolytic anemia. He was diagnosed with a stage IV, WHO type A thymoma and was treated with oral prednisolone (1 mg/kg/day) and subsequent chemotherapy. After chemotherapy, the patient underwent surgical resection of the thymoma. Hemolysis(More)
A new decoding algorithm that consists of two decoding stages to reduce the computational complexity of maximum likelihood decoding for parallel combinatory high-compaction multicarrier modulation is proposed. The first decoding stage is responsible for a preliminary decision that serves to roughly find candidate messages using the QRD-M algorithm, and the(More)
SUMMARY A new type of modulation called continuous-phase parallel-combinatory high-compaction multicarrier modulation (CPPC/ HC-MCM) is proposed. CPPC/HC-MCM employs the technique of continuous-phase modulation (CPM) and avoids the formation of amplitude gaps between two successive signals to enhance the spectral efficiency of conventional PC/HC-MCM.(More)
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