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The Arg/N-end rule pathway targets for degradation proteins that bear specific unacetylated N-terminal residues while the Ac/N-end rule pathway targets proteins through their N(α)-terminally acetylated (Nt-acetylated) residues. Here, we show that Ubr1, the ubiquitin ligase of the Arg/N-end rule pathway, recognizes unacetylated N-terminal methionine if it is(More)
Acinetobacter baumannii is an important human pathogen that can form biofilms and persist under harsh environmental conditions. Biofilm formation and virulence are modulated by blue light, which is thought to be regulated by a BLUF protein, BlsA. To understand the molecular mechanism of light sensing, we have used steady-state and ultrafast vibrational(More)
Sexual dimorphism can be seen at many levels across the animal kingdom. In humans, it is still surrounded by much controversy and myth. While many sex-specific differences are remarkably obvious, others are subtle, complex, or even puzzling. Psychological and socio-cultural factors can also play a role by heavily influencing the perception of these(More)
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